Can you take tramadol if you have seizures?

Tramadol should be avoided in all patients who have epilepsy or are susceptible to seizures unless there are compelling circumstances.

Which classes of antidepressants should be avoided in patients who are taking tramadol?

As tramadol inhibits serotonin and noradrenaline reuptake, combinations with selective serotonin reuptake inhibitors (SSRIs) or serotonin noradrenaline reuptake inhibitors (SNRIs) are likely to have additional adverse effects without added benefits.

Why should you not take tramadol with antidepressants?

Tramadol can cause serotonin syndrome if taken with some antidepressants. Selective serotonin reuptake inhibitors (SSRIs) are medicines commonly prescribed for treating depression. They work by increasing the level of serotonin in the brain, according to Mayo Clinic.

Can you mix antidepressant with tramadol?

Tramadol can be safely combined with antidepressants; however, monitoring and counseling patients are prudent when starting a new serotonergic agent or when doses are increased.

Can tramadol be taken with citalopram?

Using citalopram together with traMADol can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision.

How much tramadol can cause seizure?

Seizures occurred in the first 24-48 hours in subjects taking 500-750 mg/day of tramadol and between 2-365 days after tramadol intake in subjects taking tramadol within the therapeutic range (50-300mg/day) (8).

What antidepressant works with tramadol?

Dual action antidepressants mirtazapine (Remeron), duloxetine (Cymbalta), and most notably venlafaxine (Effexor), which tramadol is closely related to in structure, also inhibit NE and 5HT reuptake.

Which antidepressant Can you take with tramadol?

Tramadol as a factor. With regard to the antidepressant interactions, SS has been reported with combinations of tramadol and the following: fluoxetine,26–28 sertraline,29–31 paroxetine,32–35 citalopram,36 fluvoxamine,37 venlafaxine,38,39 and TCAs.