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How much does Neratinib cost?

How much does Neratinib cost?

The cash price of neratinib is about $10,400 for 30 days at full dose.

What kind of drug is Neratinib?

Neratinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.

What is Neratinib used for?

On July 17, the Food and Drug Administration (FDA) approved neratinib (Nerlynx™) to prevent recurrence in patients with early-stage HER2-positive breast cancer who have finished at least 1 year of post-surgery trastuzumab (Herceptin®) therapy.

How do you interpret HER2 results?

Testing for HER2 status The IHC gives a score of 0 to 3+ that measures the amount of HER2 proteins on the surface of cells in a breast cancer tissue sample. If the score is 0 to 1+, it’s considered HER2-negative. If the score is 2+, it’s considered borderline. A score of 3+ is considered HER2-positive.

Is Neratinib a chemotherapy drug?

Neratinib is considered a “targeted therapy” medication, not a chemotherapy drug. To date, cancer treatment has focused primarily on killing rapidly dividing cells. This is because a major feature of cancer cells is that they divide rapidly.

Is Neratinib FDA approved?

On February 25, 2020, the Food and Drug Administration approved neratinib (NERLYNX, Puma Biotechnology, Inc.) in combination with capecitabine for adult patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2 based regimens in the metastatic setting.

How long do you take Neratinib?


  1. Adults—At first, 240 milligrams (mg) (6 tablets) taken once a day for at least 1 year.
  2. Children—Use and dose must be determined by your doctor.

How effective is Nerlynx?

After two years, 94.2 percent of patients treated with Nerlynx had not experienced cancer recurrence or death compared with 91.9 percent of patients receiving placebo.

Does Nerlynx cause weight gain?

The most common adverse reactions (more than 5%) were diarrhea, nausea, abdominal pain, fatigue, vomiting, rash, stomatitis, decreased appetite, muscle spasms, dyspepsia, increased AST or ALT, nail disorder, dry skin, abdominal distention, decreased weight, and urinary tract infection.

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