What are the doses of infliximab?
What are the doses of infliximab?
The recommended dosage of REMICADE® is 5 mg/kg given as an intravenous induction regimen at 0, 2, and 6 weeks, followed by a maintenance regimen of 5 mg/kg every 8 weeks thereafter for the treatment of active PsA. REMICADE® can be used with or without methotrexate.
What is Revellex used for?
Revellex® (infliximab) is a monoclonal antibody that specifically targets tumor necrosis factor-alpha (TNF-α), which has been shown to play a role in Crohn’s disease, rheumatoid arthritis, ankylosing spondylitis, ulcerative colitis, paediatric Crohn’s disease, psoriatic arthritis, and plaque psoriasis.
Can Remicade be given every 4 weeks?
For patients who have an incomplete response, consideration may be given to adjusting the dosage up to 10 mg/kg IV every 8 weeks or treating as often as every 4 weeks, bearing in mind that risk of serious infections is increased at higher doses per infusion or more frequent dosing.
What weight should I use for infliximab?
With regard to dosing of infliximab in inflammatory bowel disease, as can be seen in Table 2, international and national consensus statement/guidelines recommend a dosage of 5 mg kg−1 body weight given in a 0-2-6-weeks induction regimen and followed by maintenance dosing every 8 weeks [4, 7].
How long do you have to take infliximab?
HOW LONG WILL I BE ON INFLIXIMAB? Some patients with Ulcerative Colitis may require ‘rescue therapy’ in order to try to prevent unplanned surgery, this treatment typically last three months or more. However, most patients with IBD will be treated for a minimum of 12 months.
What is Revellex?
REVELLEX is intended for the treatment of rheumatoid arthritis, ankylosing spondylitis, psoriatic. arthritis, psoriasis, Crohn’s disease and ulcerative colitis, with the aim to reduce inflammatory. activity. The active substance infliximab, is a human-mouse monoclonal antibody.
How often can you have infliximab?
The recommended dose is 5mg of infliximab for every kilogram you weigh. How often will I need an infusion? Most people with IBD have an initial infusion followed by another infusion at two weeks and a third at six weeks.
Can infliximab make you lose weight?
Patients with [Crohn disease] and those who receive any dose of [infliximab] are more likely to experience increased weight gain. When starting treatment, those with more severe disease, as indicated by lower albumin and hematocrit and higher [C-reactive protein], are likely to gain more weight.