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What is neutral genetic variation?

What is neutral genetic variation?

Neutral genetic variation is described as that which is unaffected by natural selection.

What is selectively neutral?

A situation in which different alleles of a certain gene confer equal fitness.

What are selectively neutral mutations?

A mutation whose fixation is independent of natural selection is termed a neutral mutation. Therefore selective neutrality of a mutation can be defined by independence of its fixation from natural selection.

What is an example of a neutral variation?

For example, bovine and human insulin, while differing in amino acid sequence are still able to perform the same function. The amino acid substitutions between species were seen therefore to be neutral or not impactful to the function of the protein.

What causes neutral mutation?

Thus, mutations that do not affect an individual’s fitness, i.e., neutral mutations, are driven by genetic drift and remain unaffected by natural selection. The neutral gene hypothesis is based upon the fact that alleles have equal fitness, and thus the process of natural selection does not apply to them.

What is meant by neutral evolution?

History. The neutral theory of molecular evolution contends that at the molecular level, most evolutionary changes and polymorphisms within species are not caused by natural selection, but by random genetic drift. The theory was first put forward by M. Kimura in l968.

What are neutral mutations in humans?

The majority of mutations have neither negative nor positive effects on the organism in which they occur. These mutations are called neutral mutations. Examples include silent point mutations, which are neutral because they do not change the amino acids in the proteins they encode.

What is the neutral theory in biology?

The neutral theory of molecular evolution contends that at the molecular level, most evolutionary changes and polymorphisms within species are not caused by natural selection, but by random genetic drift.

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