What is tyrosinase protein?

Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation. It is found inside melanosomes which are synthesized in the skin melanocytes. In humans, the tyrosinase enzyme is encoded by the TYR gene.

What is the enzyme responsible for melanogenesis?

Abstract: Melanogenesis is a biosynthetic pathway for the formation of the pigment melanin in human skin. A key enzyme, tyrosinase, catalyzes the first and only rate-limiting steps in melanogenesis, and the down-regulation of enzyme activity is the most reported method for the inhibition of melanogenesis.

What happens during melanogenesis?

Melanogenesis is the complex process by which the pigment melanin is produced in melanosomes by melanocytes. There are two distinct types of melanin: black to brown eumelanin and yellow to reddish-brown pheomelanin. The ratio of eumelanin to pheomelanin determines the color of the hair, skin, and eyes.

What does melanogenesis inhibitor do?

Directly Inhibiting Tyrosinase Catalytic Activity. The most common target for melanogenesis inhibitors is direct inhibition of tyrosinase catalytic activity. Moreover, in the view of clinical applications in cosmetics and pharmaceuticals, tyrosinase inhibitors are the most popular and wildly-used hypopigmenting agents.

What is tyrosinase used for?

Tyrosinase is responsible for the first step in melanin production. It converts a protein building block (amino acid) called tyrosine to another compound called dopaquinone.

What enzyme converts tyrosine to melanin?

Tyrosinase
Tyrosinase is responsible for the first step in melanin production. It converts a protein building block (amino acid) called tyrosine to another compound called dopaquinone.

Does tyrosinase reduce melanin production?

Melanocytes are what give your skin, hair, eye their color. In this post, we list out some of the best tyrosinase inhibitors that reduce the production of melanin and therefore are widely used in anti-hyperpigmentation skincare products.

What do tyrosinase inhibitors do?

Using a Tyrosinase Inhibitor will help protect your skin and prevent you from forming hyperpigmentation and oftentimes hyperpigmentation is lying underneath the skin and will surface later-on in life. You can prevent this hyperpigmentation from happening or from surfacing altogether.

Is tyrosinase a protein?

Tyrosinase-related protein, also known as catalase B and gp75, is a melanocyte-specific protein whose precise function is not well understood. Various roles may include stabilizing tyrosinase, regulating melanin production through peroxide levels, and determining the shape of melanosomes.

What protein removes dark spots?

Enriched with the goodness of mega-3 fatty acids, salmon is an A1 choice to protect skin against dark spots!