Can you IV push labetalol?

Labetalol injection is intended for I.V. use in hospitalised patients. Bolus injection: If it is essential to reduce the blood pressure quickly a dose of 50 mg should be given by I.V.

Does labetalol IV push need to be diluted?

A labetalol infusion solution containing 1mg/ml needs to be used. This solution can be made by diluting the contents of four 10ml ampoules (200mg) to 200ml with Sodium Chloride and Dextrose Injection, 5% dextrose Intravenous Infusion, Potassium Chloride and Glucose solution or Ringer Lactate.

Why is labetalol contraindicated in pulmonary edema?

We conclude that the incidence of pulmonary edema in patients with severe preeclampsia who are treated with labetalol appears to be a result of an increase in third space fluid accumulation as a manifestation of the severity of their disease, not a direct effect of the drug on cardiac performance.

What should you assess before giving labetalol?

Assess heart rate, ECG, and heart sounds, especially during exercise (See Appendices G, H). Report any rhythm disturbances or symptoms of increased arrhythmias, including palpitations, chest discomfort, shortness of breath, fainting, and fatigue/weakness.

How do you give labetalol IV bolus?

Administer labetalol 20mg as a slow IV bolus over 2 minutes. . The maximal effect usually occurs within 5 minutes of each injection. Once BP has stabilised monitor BP hourly for 4 hours then return to usual pre-eclampsia regimen.

How do you administer IV labetalol infusion?

Administration of continuous IV infusion: Dilute 100mg of labetalol in 30mL of sodium chloride 0.9% and delivery through a syringe driver. Infuse via a dedicated peripheral or central lumen. Do not attach to a two way infusion as an inadvertent bolus may be delivered. Commence infusion at 10 mL/hour (20mg/hour).

What are contraindications of labetalol?

The following conditions are contraindicated with this drug….Conditions:

• diabetes.
• depression.
• myasthenia gravis, a skeletal muscle disorder.
• complete heart block.
• partial heart block.
• sinus bradycardia.
• sudden and serious symptoms of heart failure called acute decompensated heart failure.
• significantly low blood pressure.

Can labetalol cause edema?

fluid retention (edema), shortness of breath, and rarely, postural hypotension (a rapid decrease in blood pressure when going from the lying or seated position to the standing position that may cause light-headedness or fainting).

Does labetalol cause fluid retention?

Dizziness, nausea, fatigue, tingling of the scalp or skin, and fluid retention. Labetalol lowers blood pressure more when standing than when sitting or lying down. This may cause postural hypotension (a noticeable drop in blood pressure when going from a sitting to a standing position).

How do you take labetalol IV?

Commence treatment with IV bolus. Administer labetalol 20mg as a slow IV bolus over 2 minutes. . The maximal effect usually occurs within 5 minutes of each injection. Once BP has stabilised monitor BP hourly for 4 hours then return to usual pre-eclampsia regimen.