# What is a PopG?

## What is a PopG?

PopG is a very basic population genetics simulation program developed at the University of Washington. It is a stochastic simulation: if the fitness for Aa is 0.5, then each individual with genotype Aa has a 50% chance of survival. This means that sometimes a few more than 50% will survive, sometimes a few less.

How do I install PopG?

Installing PopG

2. A downwards-pointing animated arrow in the lower-left portion of the browser window will move, pointing to a tab there called PopG. zip.
3. PopG.
4. Click (or if this does not work, double-click) on the PopG.
5. Move that folder to where you want it to be.

### What happens if a population is not in Hardy Weinberg equilibrium?

No natural selection. If any one of these assumptions is not met, the population will not be in Hardy-Weinberg equilibrium. Instead, it may evolve: allele frequencies may change from one generation to the next.

What are the 5 assumptions for Hardy-Weinberg?

The Hardy–Weinberg principle relies on a number of assumptions: (1) random mating (i.e, population structure is absent and matings occur in proportion to genotype frequencies), (2) the absence of natural selection, (3) a very large population size (i.e., genetic drift is negligible), (4) no gene flow or migration, (5) …

## What are the 5 conditions of Hardy-Weinberg?

The conditions to maintain the Hardy-Weinberg equilibrium are: no mutation, no gene flow, large population size, random mating, and no natural selection. The Hardy-Weinberg equilibrium can be disrupted by deviations from any of its five main underlying conditions.

What is Hardy-Weinberg used for?

Hardy-Weinberg Equilibrium (HWE) is used to estimate the number of homozygous and heterozygous variant carriers based on its allele frequency in populations that are not evolving.

### What is the purpose of the Hardy-Weinberg principle?

The Hardy-Weinberg equation is a mathematical equation that can be used to calculate the genetic variation of a population at equilibrium. In 1908, G. H. Hardy and Wilhelm Weinberg independently described a basic principle of population genetics, which is now named the Hardy-Weinberg equation.

How do you calculate Hardy-Weinberg?

The Hardy-Weinberg equation used to determine genotype frequencies is: p2 + 2pq + q2 = 1. Where ‘p2’ represents the frequency of the homozygous dominant genotype (AA), ‘2pq’ the frequency of the heterozygous genotype (Aa) and ‘q2’ the frequency of the homozygous recessive genotype (aa).

## What are the 5 Hardy-Weinberg conditions?

There are five basic Hardy-Weinberg assumptions: no mutation, random mating, no gene flow, infinite population size, and no selection. If the assumptions are not met for a gene, the population may evolve for that gene (the gene’s allele frequencies may change).

What are the 5 Hardy-Weinberg rules?

### How is the Hardy-Weinberg formula useful for identifying evolution?

By describing specific ideal conditions under which a population would not evolve, the Hardy-Weinberg principle identifies variables that can influence evolution in real-world populations. 