What is UFUR?

It is an orally active agent for advanced non-small-cell lung cancer (NSCLC) in those who have failed a previous platinum-based regimen and taxane treatment. UFUR (Tegafur/Uracil) is effective agent against chemo-naïve NSCLC. It has anti-angiogenesis effect when used as long-term low dose treatment.

What is tegafur used for?

Tegafur-uracil is a chemotherapy drug that is given as a treatment for some types of cancer, especially BOWEL CANCER. It is also sometimes called Uftoral. This information describes tegafur-uracil, how it is given and some of the possible side effects.

What class of drug is tegafur?

Tegafur is an antineoplastic agent that belongs in the class of pyrimidine analogues.

How long can I take capecitabine?

These doses are taken for 2 weeks, followed by 1 week rest, given as 3 weeks cycle. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.

What is leucovorin used to treat?

Leucovorin is used as an antidote to the harmful effects of methotrexate (a cancer medicine) that is given in high doses. It is used also to prevent or treat certain kinds of anemia. Leucovorin acts the same way in the body as folic acid, which may be low in these patients.

What is the difference between folic acid and leucovorin?

Leucovorin is also called folinic acid. It’s very similar, but not the same as folic acid. Folic acid is an over-the-counter dietary supplement for low folate levels, whereas leucovorin is only available by prescription, and it treats side effects from methotrexate and other anti-folate medications.

Is irinotecan better than oxaliplatin?

The response rate of oxaliplatin group was higher than that of irinotecan group (relative risk (RR) = 0.82, 95% confidence interval (95%CI) (0.70, 0.96), P = 0.01), and the median overall survival of oxaliplatin group was longer by 2.04 months than that of irinotecan group (95%CI (-3.54, -0.54), P = 0.008).