What should progesterone be before FET?

We propose that maintenance of levels between 10 and 20 ng/ml prior to implantation will maximize implantation and ongoing pregnancy rates for FETs using single euploid embryos (ESTEET).

How long are you on estrogen before frozen embryo transfer?

A dose of estrogen is usually administered for 14 days, although shorter or longer cycles may be used, Estrace® is the most common form of estrogen we use. This is a pill containing 2 mg of estradiol, the same hormone produced by the ovaries. We will have you take one pill twice a day for about 14 days.

What was your FET protocol?

FET uses embryos (fertilized eggs) that have been frozen. During the FET cycle, your embryos are thawed and placed into your uterus. This is done at a time in your menstrual cycle that best supports a pregnancy. You will be given hormones to help your endometrium (lining of your uterus) accept the embryos.

How many days after period is frozen embryo transfer?

If you are having an FET (frozen embryo transfer), that means you have embryos frozen from a previous IVF cycle. Your embryos were most likely frozen five, six, or in some cases, seven days after egg retrieval. In cases like this, the process can take 3-4 weeks from the time you get your menses.

What level should progesterone be on day 21?

Typically, day 21 to 23 serum progesterone concentrations of more than 10 ng/mL indicate normal ovulation and concentrations below 10 ng/mL suggest anovulation, inadequate luteal phase progesterone production, or inappropriate timing of sample collection.

Can too much progesterone affect implantation?

“Higher progesterone levels may make it more difficult for embryos to implant — that is, adhere to the wall of the uterus to establish pregnancy — possibly due to premature maturation of the uterine lining.”

How long do you take progesterone after embryo transfer?

Progesterone production is the domain of the ovary until the placenta takes over progesterone production at around 8-10 weeks gestational age. Because of the estimated timing and the desire to be conservative, most IVF clinics in the US recommend progesterone supplementation for 8-10 weeks after egg retrieval/FET.

Can you have too much progesterone IVF?

Higher progesterone levels may make it more difficult for embryos to implant. The new findings may prompt physicians to suggest that patients with high progesterone levels at egg retrieval freeze their embryos and wait for a subsequent cycle to transfer them, said Wang.

What does progesterone do for FET?

Progesterone matures the uterine lining and makes it receptive to an embryo to implant. Once the progesterone is begun, there is a certain “window of implantation” during which the embryo must be transferred. The stage of the embryo must match the stage of development of the uterus.

Why do frozen embryos take longer to implant?

According to the researchers, the success of frozen embryos can be explained by the fact that frozen embryos take longer than fresh embryos to implant in the uterus. This is important because it allows hormone levels in the uterus to return to normal before the embryo is implanted.