How much does tolvaptan cost per month?

At a drug cost of $5,760 per month, tolvaptan cost $744,100 per QALY gained compared to standard care.

What is the brand name for tolvaptan?

Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V2) antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic …

Is tolvaptan generic?

May 20, 2020 – Alkem/Ascend and Apotex launched AB-rated generic versions of Otsuka’s Samsca (tolvaptan) 30 mg tablets.

How long can you take tolvaptan?

[04-30-2013] The U.S. Food and Drug Administration (FDA) has determined that the drug Samsca (tolvaptan) should not be used for longer than 30 days and should not be used in patients with underlying liver disease because it can cause liver injury, potentially requiring liver transplant or death.

How much does tolvaptan cost in Canada?

Health Canada recently released a safety warning for tolvaptan in patients with polycystic kidney disease who developed serious liver injuries. The daily cost of tolvaptan treatment is $250.

What is the best medicine for low sodium?

SAMSCA is a prescription medicine used to help increase low sodium levels in the blood, in adults with conditions such as heart failure, and certain hormone imbalances. SAMSCA helps raise salt levels in your blood by removing extra body water as urine.

Is tolvaptan available?

Tolvaptan is also available as brand 15 mg tablets (Samsca) and brand 15 mg and 30 mg tablets (Jynarque®). Samsca carries a boxed warning to initiate and re-initiate in a hospital and monitor serum sodium; and not for use for autosomal dominant polycystic kidney disease.

Is tolvaptan available in Canada?

announced that JINARC™ (tolvaptan), is now commercially available for use in Canada. JINARC™ is indicated to slow the progression of kidney enlargement in adults with autosomal dominant polycystic kidney disease (ADPKD).